Neurometabolic Coupling in the Lateral Geniculate Nucleus Changes With Extended Age

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Neurometabolic coupling in the lateral geniculate nucleus changes with extended age.

Attempts have been made in various studies to identify and trace changes in function in the aging visual system. Some results are conflicting and we report here a unique approach in an attempt to resolve selected issues. We have estimated neurometabolic coupling in the central visual pathway in young and old cats. Our technique provides high resolution simultaneous measurements of neuronal acti...

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The relationships between neural and metabolic processes in activated brain regions are central to the interpretation of noninvasive imaging. To examine this relationship, we have used a specialized sensor to measure simultaneously tissue oxygen changes and neural activity in colocalized regions of the cat's lateral geniculate nucleus (LGN). Previous work with this sensor has shown that a decre...

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2010

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.00270.2010